The prosperous goitre: basedow’s bonanza-graves’ disease

Coeliac disease and goitre.

Two cases of coeliac disease associated with thyroid enlargement are presented. One had a large simple adenomatous goitre which was removed surgically and the other had histological confirmation of lymphadenoma (Hashimoto's disease).

[Graves' disease].

Graves' Disease.

Graves’ disease was first recognized in the 19th century as a syndrome comprising an enlarged and overactive thyroid gland, an accelerated heart rate, and ocular abnormalities (Fig. 1). Critical for our current understanding of this disease was the discovery of its autoimmune basis, which results from complex interactions between genetic and environmental factors.1,2 Graves’ disease has adverse...

Graves’ Disease

Copyright © 2008 Massachusetts Medical Society. A 23-year-old woman presents with palpitations. Over the past 6 months, she has reported loose stools, a 10-lb (4.5-kg) weight loss despite a good appetite and food intake, and increased irritability. She appears to be anxious and has a pulse of 119 beats per minute and a blood pressure of 137/80 mm Hg. Her thyroid gland is diffusely and symmetric...

The Eye in Graves' Disease.

Classification "Lid lag" True lid lag is virtually specific for hyperthyroidism. It is probably due to increased tone in the levator palpebrae superioris and gives rise to the "staring" appearance. It can be elicited by making the subject follow movements of the finger rapidly up and down. The upper lid can Ibe observed to lag behind the movement of the eyeballs, especially in a downward direct...